Victor J. Avila-Quintero

Oct 25, 2023 | jamanetwork.com | Luis C. Farhat |Jose Flores |José Flores |Victor J. Avila-Quintero

Key PointsQuestion  Are unlicensed doses of stimulants associated with positive treatment outcomes in adults with attention-deficit/hyperactivity disorder (ADHD)? Findings  In this systematic review and meta-analysis of group averages, unlicensed doses of stimulants were associated with small, possibly nonclinically meaningful, additional reductions of ADHD symptoms and increased risk of treatment discontinuation due to adverse events in comparison with licensed doses of these medications.