Weidong Tian

4 weeks ago | science.org | Qiming Liu |Yao Ma |Hui Li |Weidong Tian

AbstractShort tandem repeats (STRs), characterized by high–copy number mutations, represent one of the fastest-evolving genomic elements. However, human-specific expanded STRs (heSTRs) have lacked comprehensive genome-wide characterization. Leveraging 148 human and 26 nonhuman primate haploid genomes, we identified 8813 heSTRs with robust expansions in copy number distributions. Our analysis revealed notable associations between heSTRs and brain- and neuron-specific distal regulatory signals.

Nov 30, 2024 | mdpi.com | Baolai Wang |Weidong Tian |Chao Wang |Qi Wang

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Jul 8, 2024 | pubs.rsc.org | Xuan Wang |Qiuyu Chen |JiaYi Li |Weidong Tian

Recent advances of functional modules for tooth regeneration Dental diseases, such as dental caries and periodontal disorders, constitute a major global health challenge, affecting millions worldwide and often resulting in tooth loss. Traditional dental treatments, though beneficial, typically cannot fully restore the natural functions and structures of teeth. This limitation has prompted growing interest in innovative strategies for tooth regeneration methods.