Weihang Zhang

May 21, 2024 | biorxiv.org | Xin Zeng |Shu Liu |Bowen Liu |Weihang Zhang

AbstractMotivation: Understanding the dynamics of gene regulatory networks (GRNs) across various cellular states is crucial for deciphering the underlying mechanisms governing cell behavior and functionality.

Dec 1, 2023 | biorxiv.org | Weihang Zhang |Yang Cui |Bowen Liu |Martin Lopez

AbstractReliable cell type annotations are crucial for investigating cellular heterogeneity in single-cell omics data. Although various computational approaches have been proposed for single-cell RNA sequencing (scRNA-seq) annotation, high-quality cell labels are still lacking in single-cell ATAC sequencing (scATAC-seq) data, because of extreme sparsity and inconsistent chromatin accessibility between datasets.