Weihua Guan

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Articles

Association between Circulating T Cells and the Gut Microbiome in Healthy Individuals: Findings from a Pilot Study

Jun 21, 2024 | mdpi.com | You Shen |Weihua Guan |Guillaume Onyeaghala |Sithara Vivek

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Effect of Intrapersonal and Interpersonal Behavior Change Strategies on Physical Activity

Feb 29, 2024 | jamanetwork.com | Siobhan McMahon |Beth Lewis |Weihua Guan |Qi Wang

Key PointsQuestion Can combining intrapersonal and/or interpersonal behavior change strategies (BCSs) with physical activity (PA) interventions promote sustained increases in total PA among community-dwelling older adults who are insufficiently active?
Literary Identification of Differentially Hydroxymethylated DNA Regions for Type 2 Diabetes Mellitus: A Scoping Minireview

Feb 3, 2024 | mdpi.com | Weihua Guan |Jun Dai |Fue Chee Vue |Ryan Anh Minh

All articles published by MDPI are made immediately available worldwide under an open access license. No specialpermission is required to reuse all or part of the article published by MDPI, including figures and tables. Forarticles published under an open access Creative Common CC BY license, any part of the article may be reused withoutpermission provided that the original article is clearly cited. For more information, please refer tohttps://www.mdpi.com/openaccess.
Probing when dCas9 tolerates DNA mismatches - Nature Biomedical Engineering

Dec 21, 2023 | nature.com | Weihua Guan

Sensing changes in ionic current as barcoded DNA translocates through solid-state nanopores allows the study of how nucleotide sequences alter the DNA-binding specificity of the catalytically inactive Cas9 ribonucleoprotein complex. Solid-state nanopores can be used to assess binding events for DNA, RNA and proteins in their folded and functional states by measuring alterations in ionic current as the molecules translocate a nanopore in the presence of an applied electric field.
High Fidelity Machine-Learning-Assisted False Positive Discrimination in Loop-Mediated Isothermal Amplification Using Nanopore-Based Sizing and Counting

Dec 1, 2023 | dx.doi.org | Ming Dong |Aneesh Kshirsagar |Anthony J Politza |Weihua Guan

Download Hi-Res ImageDownload to MS-PowerPointCite This:ACS Nano 2024, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
Developing A Baseline Metabolomic Signature Associated with COVID-19 Severity: Insights from Prospective Trials Encompassing 13 U.S. Centers

Oct 24, 2023 | mdpi.com | Kaifeng Yang |Zhiyu Kang |Weihua Guan |Sahar Lotfi-Emran

1. IntroductionDespite the success of vaccines, the ability to identify individuals at risk of severe COVID-19 disease is a persistent need. Certain individuals remain at high risk, and healthcare professionals can make better decisions with accurate information about whether or not their patients are at high risk of developing severe outcomes [1].
Programmable magnetic robot (ProMagBot) for automated nucleic acid extraction at the point of need

Jun 21, 2023 | pubs.rsc.org | Anthony J Politza |Tianyi Liu |Weihua Guan

Programmable magnetic robot (ProMagBot) for automated nucleic acid extraction at the point of need† Upstream sample preparation remains the bottleneck for point-of-need nucleic acid testing due to its complexity and time-consuming nature. Sample preparation involves extracting, purifying, and concentrating nucleic acids from various matrices. These processes are critical for ensuring the accuracy and sensitivity of downstream nucleic acid amplification and detection.
Frontiers | Number of prior live births is associated with higher arterial stiffness but not its change in older women: the atherosclerosis risk in communities study

May 23, 2023 | frontiersin.org | Alison Bonner |Weihua Guan |Abbi D. Lane-Cordova |Yolandi Breet

Introduction Cardiovascular disease (CVD) is the leading cause of death for women in the United States (U.S.), resulting in one third of all female deaths—approximately 400,000 deaths per year (1). While more than 26 million adults in the U.S. have diagnosed CVD (2), the level of undiagnosed CVD is significant, with 20% of myocardial infarctions going undetected at the time of occurrence (3).

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Weihua Guan

Articles

Association between Circulating T Cells and the Gut Microbiome in Healthy Individuals: Findings from a Pilot Study

Effect of Intrapersonal and Interpersonal Behavior Change Strategies on Physical Activity

Literary Identification of Differentially Hydroxymethylated DNA Regions for Type 2 Diabetes Mellitus: A Scoping Minireview

Probing when dCas9 tolerates DNA mismatches - Nature Biomedical Engineering

High Fidelity Machine-Learning-Assisted False Positive Discrimination in Loop-Mediated Isothermal Amplification Using Nanopore-Based Sizing and Counting

Developing A Baseline Metabolomic Signature Associated with COVID-19 Severity: Insights from Prospective Trials Encompassing 13 U.S. Centers

Programmable magnetic robot (ProMagBot) for automated nucleic acid extraction at the point of need

Frontiers | Number of prior live births is associated with higher arterial stiffness but not its change in older women: the atherosclerosis risk in communities study

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