Wenxiang Cao

Mar 15, 2024 | nature.com | Steven Z. Chou |Wenxiang Cao |Thomas Pollard

Correction to: Nature Communications https://doi.org/10.1038/s41467-024-46179-x, published online 06 March 2024In this article the ‘Results’ heading was inadvertently captured as part of the subsequent subheading ‘Cryo-EM structure of a mature Arp2/3 complex branch junction at 2.7 Å resolution’. The original article has been corrected.

Mar 5, 2024 | nature.com | Steven Z. Chou |Wenxiang Cao |Thomas Pollard

AbstractArp2/3 complex nucleates branched actin filaments for cell and organelle movements. Here we report a 2.7 Å resolution cryo-EM structure of the mature branch junction formed by S. pombe Arp2/3 complex that provides details about interactions with both mother and daughter filaments. We determine a second structure at 3.2 Å resolution with the phosphate analog BeFx bound with ADP to Arp3 and ATP bound to Arp2.