Steven Z. Chou

Mar 15, 2024 | nature.com | Steven Z. Chou |Wenxiang Cao |Thomas Pollard

Correction to: Nature Communications https://doi.org/10.1038/s41467-024-46179-x, published online 06 March 2024In this article the ‘Results’ heading was inadvertently captured as part of the subsequent subheading ‘Cryo-EM structure of a mature Arp2/3 complex branch junction at 2.7 Å resolution’. The original article has been corrected.

Mar 9, 2024 | biorxiv.org | Emily Guo |Steven Z. Chou |María Lara-Tejero |Jorge Galán

AbstractThe bacterial pathogen Salmonella spp. modulates cellular processes by delivering effector proteins through its type III secretion systems. Among these effectors, SipA facilitates bacterial invasion and promotes intestinal inflammation. The mechanisms by which this effector carries out these functions are incompletely understood although SipA's ability to modulate actin dynamics is central to some of these activities. Here we report the cryo-EM structure of SipA bound to filamentous actin.

Mar 5, 2024 | nature.com | Steven Z. Chou |Wenxiang Cao |Thomas Pollard

AbstractArp2/3 complex nucleates branched actin filaments for cell and organelle movements. Here we report a 2.7 Å resolution cryo-EM structure of the mature branch junction formed by S. pombe Arp2/3 complex that provides details about interactions with both mother and daughter filaments. We determine a second structure at 3.2 Å resolution with the phosphate analog BeFx bound with ADP to Arp3 and ATP bound to Arp2.

Feb 5, 2024 | ffnews.com | Lauren Hinton |Nameer Khan |Steven Z. Chou |MENA Fintech Association

The MENA Fintech Association, the premier not-for-profit organization dedicated to serving fintech startups and established players across the Middle East and Africa, is excited to announce its new partnership with Sahm Capital Financial Company (previously known as VCFC), a leading brokerage firm licensed by Saudi Capital Market Authority (22251-25) As a leading Fintech solution provider, Sahm Capital is committed to providing Saudi users with a seamless and tailored investing experience,...

May 12, 2023 | biorxiv.org | Steven Z. Chou |Thomas Pollard

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