Wilbur Pan

Sep 11, 2024 | nature.com | Seock-Ah Im |Javier Cortés |David W. Cescon |Norikazu Masuda |Toshimi Takano |Chiun-Sheng Huang | +6 more

AbstractIn the phase 3 KEYNOTE-355 study (NCT02819518), pembrolizumab plus chemotherapy demonstrated statistically significant and clinically meaningful improvements in progression-free survival (PFS) and overall survival (OS) versus placebo plus chemotherapy among patients with previously untreated locally recurrent inoperable or metastatic triple-negative breast cancer (TNBC) and programmed cell death ligand 1 (PD-L1) combined positive score (CPS) ≥ 10 tumors.

Apr 10, 2024 | futuremedicine.com | Amin Haiderali |Min Huang |Wilbur Pan |Katherine G. Akers

Breast cancer is the most common cancer in women, with 2.3 million new cases worldwide in 2020 [1]. A subtype of breast cancer, triple-negative breast cancer (TNBC) accounts for ∼15% of all breast cancer cases and is characterized by the lack of ER, PR and HER2 [2]. TNBC has the worst prognosis among all breast cancer subtypes, with a median overall survival (OS) of 13 months in patients with metastatic TNBC compared with 38 months in patients with other types of breast cancer [3].

Aug 15, 2023 | popularwoodworking.com | Wilbur Pan

https://www.popularwoodworking.com/wp-content/uploads/popwood_logos-01.pngPopular Woodworking//www.popularwoodworking.com/wp-content/uploads/2020/01/01pwm0414chipbreaker-1.jpg200px200px Most bench planes come equipped to eliminate tear-out. Handplanes are great tools for creating a smooth, finish-ready surface on a board without the dust and noise from a sander.