Xavier Matias-Guiu

1 week ago | hal.science | Xavier Matias-Guiu |Universitat de Lleida |Jordi Temprana-Salvador |Pablo Lopez |Pablo López

Article Dans Une Revue Virchows Archiv Année : 2025 Implementing digital pathology: qualitative and financial insights from eight leading European laboratories Origine Fichiers éditeurs autorisés sur une archive ouverte hal-05034831 , version 1 (15-04-2025) Xavier Matias-Guiu, Jordi Temprana-Salvador, Pablo Garcia Lopez, Solene-Florence Kammerer-Jacquet, Nathalie Rioux-Leclercq, et al..

2 months ago | nature.com | Oscar Maiques |Olivia Courbot |Yanbo Liu |Vittoria Graziani |Youssef Arafat |Irene Rodríguez-Hernández | +8 more

AbstractThe extracellular matrix (ECM) controls tumour dissemination. We characterise ECM organization in human and mouse tumours, identifying three regions: tumour body, proximal invasive front and distal invasive front. Invasive areas show increased matrix density, fibre thickness, length, and alignment, with unique radial fibre orientation at the distal invasive front correlating with amoeboid invasive features.