Xavier Montalban

Oct 7, 2024 | neurologylive.com | Xavier Montalban |Isabella Ciccone

WATCH TIME: 4 minutes"We are now moving towards a more biological diagnosis of multiple sclerosis, and this is essential. This is happening as well in other neurodegenerative diseases such as Parkinson and Alzheimer [disease].

Jun 19, 2024 | mdpi.com | Mireia Castillo |Xavier Montalban |María Dema |Herena Eixarch

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Mar 4, 2024 | journals.sagepub.com | Xavier Montalban |Jens Kuhle |Pascal Benkert |Karolina Piasecka-Stryczynska

AbstractEvobrutinib – an oral, central nervous system (CNS)-penetrant, and highly selective Bruton’s tyrosine kinase inhibitor – has shown efficacy in a 48-week, double-blind, Phase II trial in patients with relapsing MS. Report results of the Phase II open-label extension (OLE; up to week 192 from randomisation) and a cerebrospinal fluid (CSF) sub-study.

Jan 1, 2024 | nature.com | Jiwon Oh |Luca Capezzuto |Lito Kriara |Johan van Beek |Corrado Bernasconi |Xavier Montalban | +6 more

AbstractFloodlight Open was a global, open-access, digital-only study designed to understand the drivers and barriers in deployment and use of a smartphone app in a naturalistic setting and broad study population of people with and without multiple sclerosis (MS).

Jul 22, 2023 | mdpi.com | Sunny Malhotra |Agustín Pappolla |Xavier Montalban |Manuel Comabella

3. Liquid Biopsy in Neurological DiseasesA wide range of techniques have been employed to study liquid biopsy in neurological diseases. These techniques include miRNA arrays for miRNA profiling, highly sensitive next-generation sequencing (NGS) for RNA sequencing, reduced representation bisulfite sequencing (RRBS), and Infinium MethylationEPIC BeadChip (EPIC) for analysing methylation patterns.