Xenab Ahmadpoor

May 6, 2024 | onlinelibrary.wiley.com | Yuchen He |Yishu Fan |Yumin Wang |Xenab Ahmadpoor

1 INTRODUCTION Lysosomes, first described by Dr. de Duve about 70 years ago, have been recognized as the primary degradative compartment in eukaryotic cells.1 Studies in the past have revealed their characteristics as highly acidic, dynamic, heterogeneous single membrane cellular organelles with varying sizes, locations, morphology, enzyme content, substrates, and functions.