Xenia Parisi

Aug 16, 2024 | jcp.bmj.com | Xenia Parisi |Jacob Bledsoe

General conceptsNeutropenia is generally defined as an absolute neutrophil count (ANC) <1500 cells/µL in adults and children over 1 year of age, but thresholds vary by age and ethnicity.7 8 The risk for infection correlates inversely with ANC. Severe neutropenia, an ANC<500 cells/µL, is associated with a high risk of overwhelming bacterial infection and mortality, even if optimally managed.

Apr 8, 2024 | jcp.bmj.com | Xenia Parisi |Jacob Bledsoe

Handling editor Vikram Deshpande. X @XeniaParisiContributors XP and JRB both contributed significantly to the conceptualisation and writing of this manuscript. Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors. Competing interests JRB serves as a consultant for X4 Pharmaceuticals and has a research agreement with X4 Pharmaceutical on flow cytometric features of neutropenia syndromes.