Xiangxi Wang

Jan 12, 2025 | nature.com | Linlin Bao |Xiangxi Wang

AbstractThe global spread of Severe Acute Respiratory Syndrome Coronavirus 2. (SARS-CoV-2) and its variant strains, including Alpha, Beta, Gamma, Delta, and now Omicron, pose a significant challenge. With the constant evolution of the virus, Omicron and its subtypes BA.1, BA.2, BA.3, BA.4, and BA.5 have developed the capacity to evade neutralization induced by previous vaccination or infection.

Apr 6, 2024 | biorxiv.org | Ling Zhu |Zuzanna Pietras |Xiangxi Wang |Marion Pichon

AbstractParechoviruses, including Parechovirus A that infects humans as well as Parechovirus B (formerly Ljungan virus) and Parechovirus C (formerly Sebokele virus) that infect rodents, belong to a group of picornaviruses whose 2A proteins, instead of being proteases, contain a conserved H-box and NC-motif and are homologous to a small cellular lipid-modifying enzyme (PLAAT3) that acts as a host factor, enabling the picornavirus life cycle.

Oct 9, 2023 | nature.com | Jianwei Wang |Jian Lu |Xiangxi Wang

Correction to: Cell Discovery (2023) 9:78During the final submission of this manuscript, we inadvertently misplaced the Supplementary Fig. S4 as the Supplementary Fig. S5. The correct Supplementary Fig. S5 is shown as below. We are sorry for any inconveniences that might cause.

Jul 28, 2023 | nature.com | Jianwei Wang |Jian Lu |Xiangxi Wang

AbstractThe bat coronaviruses (CoV) BANAL-20-52 and BANAL-20-236 are two newly identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) closely related coronaviruses (SC2r-CoV) and the genome of BANAL-20-52 shares the highest homology with SARS-CoV-2. However, the risk of their potential zoonotic transmission has not been fully evaluated.