Zuzanna Pietras

Apr 6, 2024 | biorxiv.org | Ling Zhu |Zuzanna Pietras |Xiangxi Wang |Marion Pichon

AbstractParechoviruses, including Parechovirus A that infects humans as well as Parechovirus B (formerly Ljungan virus) and Parechovirus C (formerly Sebokele virus) that infect rodents, belong to a group of picornaviruses whose 2A proteins, instead of being proteases, contain a conserved H-box and NC-motif and are homologous to a small cellular lipid-modifying enzyme (PLAAT3) that acts as a host factor, enabling the picornavirus life cycle.