Xiaochen Bai

Nov 25, 2024 | nature.com | Amika Singla |Ran Song |Daniel Kramer |Andrew Lemoff |Xiaochen Bai |Zhe Chen | +2 more

AbstractDuring endosomal recycling, Sorting Nexin 17 (SNX17) facilitates the transport of numerous membrane cargo proteins by tethering them to the Retriever complex. Despite its importance, the mechanisms underlying this interaction have remained elusive. Here, we provide biochemical, structural, cellular, and proteomic analyses of the SNX17-Retriever interaction.

Nov 25, 2024 | nature.com | Amika Singla |Ran Song |Daniel Kramer |Andrew Lemoff |Xiaochen Bai |Zhe Chen | +2 more

AbstractDuring endosomal recycling, Sorting Nexin 17 (SNX17) facilitates the transport of numerous membrane cargo proteins by tethering them to the Retriever complex. Despite its importance, the mechanisms underlying this interaction have remained elusive. Here, we provide biochemical, structural, cellular, and proteomic analyses of the SNX17-Retriever interaction.