Xiaokang Zhu

Jun 7, 2024 | nature.com | Hang Sun |Bingwei Yang |Xiaokang Zhu |Erqun Song |Cong Liu

AbstractAmyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the dysfunction and progressive death of cerebral and spinal motor neurons. Preliminary epidemiological research has hinted at a relationship between environmental risks and the escalation of ALS, but the underlying reasons remain mostly mysterious. Here we show that nanosize polystyrene plastics (PS) induce ALS-like symptoms and illustrate the related molecular mechanism.