Hang Sun

Jun 7, 2024 | nature.com | Hang Sun |Bingwei Yang |Xiaokang Zhu |Erqun Song |Cong Liu

AbstractAmyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the dysfunction and progressive death of cerebral and spinal motor neurons. Preliminary epidemiological research has hinted at a relationship between environmental risks and the escalation of ALS, but the underlying reasons remain mostly mysterious. Here we show that nanosize polystyrene plastics (PS) induce ALS-like symptoms and illustrate the related molecular mechanism.

Sep 27, 2023 | dx.doi.org | Di Wu |Hang Sun |Bingwei Yang |Erqun Song

The biological activities of nanoparticles (NPs), which include endocytosis by macrophages and subsequent intracellular degradation and/or release, transfer to other cells, or translocation across tissue barriers, highly depend on their fate in living organisms. Yet, translocation across barriers, especially the distal “barrier-crossing” trafficking of NPs, is still unclear. The exosome (Exo) plays a crucial role in intercellular communication and biological barrier trafficking.

Aug 30, 2023 | dx.doi.org | Jing Wen |Hang Sun |Bingwei Yang |Erqun Song

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