Xingtao Zhou

1 month ago | nature.com | Yiyong Xian |Fang Liu |Zhe Zhang |Lingling Niu |Wanru Shi |Xiaoying Wang | +3 more

To compare the long-term outcomes of monovision surgery using implantable collamer lens (ICL) V4c and femtosecond laser-assisted in situ keratomileusis (FS-LASIK) in myopic patients with early presbyopia. This case series study included 48 eyes of 24 patients (male/female: 10/14, mean age 45.50 ± 3.82 years) and followed-up for 4.5 years (54.00 ± 9.77 months). Patients were examined for spherical equivalent, uncorrected distance visual acuity, corrected distance visual acuity, intraocular pressure, presbyopic add power, visual acuity (VA) (logMAR) of dominant eyes (D-eye), non-dominant eyes (nD-eye), and both eyes (Bi) at 0.4 m, 0.8 m, and 5 m, corneal wavefront aberration, and contrast sensitivity (CS). All surgeries were uneventful. The safety indices of ICL V4c group and FS-LASIK group were 1.17 ± 0.30 and 0.98 ± 0.20 (p < 0.05), and the efficacy indices were 0.79 ± 0.07 and 0.52 ± 0.07 (p < 0.05) respectively. The binocular VA (logMAR) of ICL V4c group and FS-LASIK group at 5.0 m were: 0.02 ± 0.11, 0.18 ± 0.30; 0.8 m: 0.09 ± 0.12, − 0.01 ± 0.11; 0.4 m: − 0.02 ± 0.06, − 0.03 ± 0.08, (p > 0.05 at three distances). Compared with ICL V4c group, lower CS was observed at 1.0 cpd in the FS-LASIK group (1.07 ± 0.31 vs. 0.80 ± 0.51, p = 0.043). Monovision surgery using ICL V4c and FS-LASIK provides good binocular visual acuity at near-to-far distances in myopia patients in the presbyopia age group.

Jan 2, 2025 | mdpi.com | Xingtao Zhou

1. IntroductionOpen globe injury (OGI) is a significant cause of visual morbidity and monocular vision loss across all age groups. While endophthalmitis is a rare complication of OGI, it poses a severe threat to vision. In cases where OGI is complicated by endophthalmitis, the management and visual outcomes are often more complex compared to trauma alone [1,2,3].

Aug 2, 2024 | nature.com | Xingtao Zhou

AbstractHigh myopia is a major cause of visual impairment, and genetic factors play crucial roles in the pathogenesis. We performed this study to identify candidate genes for the development of high myopia in a four-generation Chinese family with myopia. All family members with myopia and 100 healthy participants were included in this study. Data were obtained on demographics, disease history, and ocular examination results.

Dec 15, 2023 | nature.com | Xingtao Zhou

AbstractTo validate the feasibility of building a deep learning model to predict axial length (AL) for moderate to high myopic patients from ultra-wide field (UWF) images. This study included 6174 UWF images from 3134 myopic patients during 2014 to 2020 in Eye and ENT Hospital of Fudan University. Of 6174 images, 4939 were used for training, 617 for validation, and 618 for testing.

Sep 25, 2023 | mdpi.com | Yan Shen |Jiajia Wang |Xingtao Zhou |Zhiqiang Yu

1. IntroductionMyopia is one of the most common ocular diseases in Eastern Asians, especially adolescents and young people [1,2]. More than 6 million people have been reported to undergo small incision lenticule extraction (SMILE) globally since 2011, among which more than half were performed in China [3].