Xiying Mao

Dec 4, 2024 | onlinelibrary.wiley.com | Xiying Mao |Dandan Xia |Miao Xu |Yan Gao

1 Introduction Single-cell omics technologies, such as single-cell genome, epigenome, transcriptome, proteome, and metabolome, enable a deep depiction of the landscape of cellular molecular biological processes. They facilitate to describe the complete procedure of the “central dogma” and deconstructs the molecular interaction mechanism and targets from macromolecules (nucleic acids, proteins) to small molecules (metabolites), uncovering the nature of cellular heterogeneity.