Xuejun Wang

1 month ago | tandfonline.com | Xuejun Wang |Jun Chen |Han Lin |Li Zhang

AbstractAn in-depth genomic and metabolomic investigation was conducted on the endophytic fungus Penicillium turbatum BLH34, isolated from Macleaya cordata. Hybrid sequencing (Illumina-Nanopore) generated a high-quality 27.9 Mb genome (GC 48.6%) encoding 9798 proteins, with functional annotation linking 5350 genes to the NCBI non-redundant database and 3404 to KEGG pathways.

Feb 20, 2025 | nature.com | Maodian Liu |Robert Mason |Thomas Bianchi |Qianru Zhang |Xiaolong Li |Ruoyu Sun | +6 more

The Southern Ocean, one of Earth’s most productive areas, is widely recognized as a major sink for atmospheric carbon and mercury, tightly coupling primary production with the sedimentary sequestration of these elements. The impacts of climate warming on these processes, however, remain unclear. Here, we utilize 20 sediment cores from the Ross Sea, a representative ice-shelf sea in West Antarctica, to examine how Holocene warming and extensive glacial retreat influenced carbon and mercury sequestration. We find that organic carbon (OC) burial has been relatively constant over the past 12,000 years, whereas mercury burial in the Ross Embayment and open ocean exhibited three- and eightfold increases, respectively. Carbon isotopes and accumulation profiles suggest warming boosted glacial- and terrestrial-derived OC inputs to the ocean, while trace elements and biomarkers reveal a declining contribution offshore. Biomarker ratios further indicate greater remineralization of this OC in the open ocean. Consequently, enhanced OC degradation, coupled with rising external mercury inputs, drives mercury enrichment in marine sediments before reaching the seafloor. These findings imply that ongoing warming could trigger a positive feedback loop, accelerating OC degradation into CO2 and amplifying the impacts of anthropogenic mercury on Southern Ocean ecosystems. This study reveals that Holocene warming and glacial retreat in West Antarctica reduced carbon sequestration but enhanced mercury burial in Ross Sea sediments, suggesting future warming could further accelerate carbon loss and mercury accumulation.

Jan 2, 2025 | nature.com | Xuejun Wang

AbstractThe neurotoxin methylmercury in seafood threatens food safety worldwide. China has implemented stringent wastewater policies, established numerous treatment facilities and enforced rigorous water quality standards to address pollution in its waterways. However, the impact of these policies on seafood safety and methylmercury exposure remains unknown.

Nov 29, 2024 | mdpi.com | Enqiang Zhou |Yao Zhou |Xuejun Wang |Kaihua Wang

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.

Oct 14, 2024 | ahajournals.org | Xuejun Wang

Get full access to this articleView all available purchase options and get full access to this article. References1. Hofmann C, Katus HA, Doroudgar S. Protein misfolding in cardiac disease. Circulation. 2019;139:2085–2088. doi: 10.1161/CIRCULATIONAHA.118.0374172. Wang X, Wang H. Priming the proteasome to protect against proteotoxicity. Trends Mol Med. 2020;26:639–648. doi: 10.1016/j.molmed.2020.02.0073. Kurdi M, Booz GW. JAK redux: a second look at the regulation and role of JAKs in the heart.