Yanli Dong

Jan 13, 2025 | nature.com | Kunpeng Ma |Yanli Dong |Jun Zhao |Di Wu |Daohua Jiang

AbstractThe vesicular acetylcholine transporter (VAChT) has a pivotal role in packaging and transporting acetylcholine for exocytotic release, serving as a vital component of cholinergic neurotransmission. Dysregulation of its function can result in neurological disorders. It also serves as a target for developing radiotracers to quantify cholinergic neuron deficits in neurodegenerative conditions.