Ye Xu

Oct 10, 2024 | alzres.biomedcentral.com | Yaru Yang |Hongyan Qiu |Yuru Fan |Qin Zhang |Huiling Qin |Juan Wu | +9 more

Two randomized, double-blind, single-ascending-dose, phase 1 studies were conducted concurrently in China (Study CHN; NCT04973189) and Australia (Study AUS; NCT04745104). Study CHN consisted of two parts, with Part 1 involving healthy young subjects aged 18–45 years and Part 2 involving healthy elderly subjects aged 55–80 years.

Mar 8, 2023 | journals.plos.org | Ye Xu |Yong Zhang |Zhenfang Li |Shanxi Agricultural

Loading metrics Open Access Peer-reviewedResearch Article AbstractmicroRNAs (miRNAs) regulate target gene expression through their ARGONAUTE (AGO) effector protein, mainly AGO1 in Arabidopsis thaliana. In addition to the highly conserved N, PAZ, MID and PIWI domains with known roles in RNA silencing, AGO1 contains a long, unstructured N-terminal extension (NTE) of little-known function.