Yen-Yu Yang

Jan 6, 2025 | cell.com | Weili Miao |Douglas Porter |Zurab Siprashvili |Ian Ferguson |Luca Ducoli |Duy Nguyen | +11 more

Keywords RNA helicase DDX50 tissue differentiation glucose STAU1 mRNA stability Research topic(s) CP: Molecular biology Introduction RNA-binding proteins (RBPs) can promote either RNA stability or decay to mediate post-transcriptional control of RNA expression in ways important for cell fate.1,2 The DExD/H-box RNA helicases comprise a family of RBPs that exert diverse impacts on RNA, including on RNA translation, folding, and subcellular localization,3 but their impacts on RNA stability are...

Jan 6, 2025 | cell.com | Weili Miao |Douglas Porter |Zurab Siprashvili |Ian Ferguson |Luca Ducoli |Duy Nguyen | +11 more

Keywords RNA helicase DDX50 tissue differentiation glucose STAU1 mRNA stability Research topic(s) CP: Molecular biology Introduction RNA-binding proteins (RBPs) can promote either RNA stability or decay to mediate post-transcriptional control of RNA expression in ways important for cell fate.1,2 The DExD/H-box RNA helicases comprise a family of RBPs that exert diverse impacts on RNA, including on RNA translation, folding, and subcellular localization,3 but their impacts on RNA stability are...

Dec 20, 2024 | science.org | Robyn Scott |Luiza Tunes |Meng-Hsiung Hsieh |Ping Wang |Ashwani Kumar |Brijesh B Khadgi | +8 more

Published In Science AdvancesVolume 10 | Issue 51December 2024Article versionsSubmission historyReceived: 14 August 2024Accepted: 14 November 2024PermissionsRequest permissions for this article. AcknowledgmentsWe thank O. Koczy, J. Parker, and R. Setlem for contributing to preliminary studies. We are grateful for the helpful discussions with B. Xhemalce on genomic data analysis. The Structural Biology Laboratory at UT Southwestern for help with synchrotron data collection.

Oct 18, 2024 | analyticalsciencejournals.onlinelibrary.wiley.com | Zhongwen Cao |Yinsheng Wang |Yen-Yu Yang

Conflicts of Interest The authors declare no conflicts of interest. References , , , , , and . 2017. “Assessment of Label-Free Quantification in Discovery Proteomics and Impact of Technological Factors and Natural Variability of Protein Abundance.” Journal of Proteome Research 16, no. 4: 1410–1424. https://doi.org/10.1021/acs.jproteome.6b00645. , , , , , and . 2009.