Yi Medicines

Jul 28, 2023 | frontiersin.org | Yi Medicines |Jianjun Qiao |Georges Doumet Helou |Angelo V. Marzano

1 IntroductionUrticaria is a frequent allergic skin disease that occurs in the spring (1). The prevalence of urticaria in adults is about 15-23%, with the cause being undetermined in 70% of these patients (2). Chronic spontaneous urticaria (CSU) is defined as the unprovoked appearance of wheals, erythema, and severe skin pruritus, lasting less than 24 hours (as opposed to urticarial vasculitis) and relapsing for more than 6 weeks (3, 4).