Yihan Zi

Aug 14, 2024 | biorxiv.org | Eleanor Brown |Mai-Anh T Vu |Safa Bouabid |Yihan Zi

AbstractGoal-directed navigation requires animals to continuously evaluate their current direction and speed of travel relative to landmarks to discern whether they are approaching or deviating from their goal. Striatal dopamine and acetylcholine are powerful modulators of goal-directed behavior, but it is unclear whether and how neuromodulator dynamics at landmarks incorporate relative motion for effective behavioral guidance.