Yijian Huang

Sep 30, 2024 | digitalcommons.library.tmc.edu | Ziyi Li |Yijian Huang |Dattatraya Patil |Mark A. Rubin

AbstractDiagnostic tests usually need to operate at a high sensitivity or specificity level in practice. Accordingly, specificity at the controlled sensitivity, or vice versa, is a clinically sensible performance metric for evaluating continuous biomarkers. Meanwhile, the performance of a biomarker may vary across sub-populations as defined by covariates, and covariate-specific evaluation can be informative.