Yili Zhang

Dec 18, 2024 | mdpi.com | Yili Zhang

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Feb 26, 2024 | pubs.rsc.org | Yuzhen Chen |JiaJia Chen |Lin Zhong |Yili Zhang

Enantioselective synthesis of spirooxindole-pyran derivatives via remote Inverse-Electron-Demand Diels−Alder reaction of β,γ-unsaturated amides The novel construction method of 3,4’-pyran spirooxindole heterocyclic skeleton has always been the focus of attention. Herein we report the highly enantioselective inverse-electron-demand oxa-Diels−Alder cycloaddition reaction of β,γ-unsaturated pyrazole amide and N-diphenyl isatin-derived oxodiene using a bifunctional catalyst.