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Jan 10, 2025 | 
biorxiv.org | Marius Pachitariu |Lin Zhong |Alexa Gracias |Amanda Minisi
AbstractArtificial neural networks learn faster if they are initialized well. Good initializations can generate high-dimensional macroscopic dynamics with long timescales. It is not known if biological neural networks have similar properties. Here we show that the eigenvalue spectrum and dynamical properties of large-scale neural recordings in mice (two-photon and electrophysiology) are similar to those produced by linear dynamics governed by a random symmetric matrix that is critically normalized.
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Nov 13, 2024 | 
tandfonline.com | Bowen Xu |Hongye Li |Hongping Chen |Lin Zhong
AbstractObjective Atherosclerosis(AS) is a vascular disease characterized by the development of plaque in the arteries, and atrial fibrillation (AF) is a common heart arrhythmia. These two conditions share several risk factors in common, such as aging, diabetes, obesity, and hypertension. Ferroptosis is a new mode of non-apoptotic cell death that plays a key role in cardiomyocyte death and has been associated with a variety of cardiac diseases.
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Oct 29, 2024 | 
mdpi.com | Lin Zhong |Wenjun Sun |Shaohua Zhang |Qianjie Liu
1. IntroductionSuspension systems have a crucial impact on vehicle handling stability, driving safety, and ride comfort [1]. Depending on the form of control, suspension systems are categorized into three main types: passive suspension, active suspension, and semi-active suspension [2]. Passive suspensions are unable to adapt to changes in body parameters and driving conditions because the damping and stiffness coefficients are fixed to certain values.
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Oct 27, 2024 | 
biorxiv.org | Lin Zhong |Siyuan Zhang |Qiwei Li |Guanghua Xiao
AbstractT cells are the central players in antitumor immunity, and effective tumor killing depends on their ability to infiltrate into the tumor microenvironment (TME) while maintaining normal cytotoxicity. However, late-stage tumors develop immunosuppressive mechanisms that impede T cell movement and induce exhaustion. Investigating T cell migration in human tumors in vivo could provide novel insights into tumor immune escape, although it remains a challenging task.
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Oct 16, 2024 | 
nature.com | Carsen Stringer |Lin Zhong |Atika Syeda
AbstractNeurophysiology has long progressed through exploratory experiments and chance discoveries. Anecdotes abound of researchers listening to spikes in real time and noticing patterns of activity related to ongoing stimuli or behaviors. With the advent of large-scale recordings, such close observation of data has become difficult.
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Sep 19, 2024 | 
chemistry-europe.onlinelibrary.wiley.com | Weijing Niu |Jiaqi Liu |Yuwei Duan |Lin Zhong
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
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Sep 3, 2024 | 
mdpi.com | Lin Zhong |Qi He |Meng Xu |Fang-fang Chen
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Aug 30, 2024 | 
mdpi.com | Lin Zhong |Alma Tamunonengiofori Banigo |Bram Zoetebier |Marcel Karperien
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Aug 19, 2024 | 
mdpi.com | Zheng Wang |Lin Zhong |Yujue Wang |Liutao Zhao
1. IntroductionSecuring data trading [1,2,3,4,5,6] is of paramount importance in today’s interconnected digital landscape. As the volume of data exchanged across platforms and borders continues to escalate, the potential vulnerabilities and threats to data integrity and privacy also increase. Effective security measures in data trading not only protect sensitive information from unauthorized access and cyber threats but also ensure the maintenance of trust between trading partners.
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Aug 7, 2024 | 
onlinelibrary.wiley.com | Chunxiao Wang |Weihong Yan |Mengmeng Ren |Lin Zhong
1 INTRODUCTION Coronary heart disease (CHD) is one of the most common causes of sudden cardiac death in young adults today.1 However, the incidence of CHD in young adults is rapidly increasing due to obesity, smoking, and unhealthy lifestyles.2 Compared with elderly adults with CHD, young patients usually have no obvious symptoms, and the prevalence of myocardial infarction (MI) in young adults is increased due to poor management of risk factors.3 Although young patients with MI have a better...
