Yiyang Li

Mar 28, 2024 | nature.com | Yiyang Li

AbstractSpatial proteomics elucidates cellular biochemical changes with unprecedented topological level. Imaging mass cytometry (IMC) is a high-dimensional single-cell resolution platform for targeted spatial proteomics. However, the precision of subsequent clinical analysis is constrained by imaging noise and resolution. Here, we propose SpiDe-Sr, a super-resolution network embedded with a denoising module for IMC spatial resolution enhancement.

Sep 13, 2023 | nature.com | Hongbo Zhao |Haitao Dean Deng |Alexander Cohen |Jongwoo Lim |Yiyang Li |Benben Jiang | +2 more

AbstractReaction rates at spatially heterogeneous, unstable interfaces are notoriously difficult to quantify, yet are essential in engineering many chemical systems, such as batteries1 and electrocatalysts2. Experimental characterizations of such materials by operando microscopy produce rich image datasets3,4,5,6, but data-driven methods to learn physics from these images are still lacking because of the complex coupling of reaction kinetics, surface chemistry and phase separation7.