Yuanyuan Lei

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Articles

Gut microbiota alters host bile acid metabolism to contribute to intrahepatic cholestasis of pregnancy - Nature Communications

Mar 9, 2023 | nature.com | Bo Tang |Li Tang |Pan Li |Yuanyuan Lei |Qin Ouyang |Xia Chen

AbstractIntrahepatic cholestasis of pregnancy (ICP) is a female pregnancy-specific disorder that is characterized by increased serum bile acid and adverse fetal outcomes. The aetiology and mechanism of ICP are poorly understood; thus, existing therapies have been largely empiric.

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