Yun Chen

1 month ago | nature.com | Shanshan Guo |Yun Chen |Yuanyuan Dang |Victoria Aranda

In public health emergencies, there is a critical need for accurate informational and emotional support to counteract misinformation and trauma. Online Health Communities (OHCs) serve as essential resources for real-time health counseling and support. This study investigates how OHCs facilitate the acquisition of informational and emotional support, crucial for guiding informed protective decisions. By integrating the Protective Action Decision Model (PADM) with social support theory, the research examines the impact of disaster-related information on patients’ decision-making within OHCs, aiming to optimize these platforms for public health response and preparedness. The study utilizes a dataset comprising 602 doctor-patient consultation dialogues from a Chinese OHC. Through text and sentiment analysis, the study quantifies the volume of information and sentiment, which serve as indicators of the level of informational and emotional support sought by patients. Environmental and social cues related to emergency situations are measured using disaster early forecast information and the volume of social media discussions on the emergency. Multiple linear regression models are employed to analyze the impact of these cues on patients’ behaviors, specifically their informational-seeking and emotional-seeking actions. It indicates that social cues have an impact on patients’ seeking informational support, while only in the high-uncertainty public health emergency, environmental cues are positively correlated with patients’ seeking both emotional and informational support. Additionally, stakeholder actions in the context of OHCs positively moderate the influence of environmental and social cues on individual protective actions to some extent. This study advances the understanding of OHCs by applying and empirically testing the PADM in a digital health context. It also explores the varying impacts of different types of public health emergencies on patient behavior within OHCs. The findings can guide healthcare providers and OHC administrators in enhancing support mechanisms, particularly during public health emergencies.

Dec 6, 2024 | pubs.acs.org | Xiaokai Chen |Xiaodong Zhang |Yang Liu |Yun Chen

Dec 6, 2024 | dx.doi.org | Xiaokai Chen |Xiaodong Zhang |Yang Liu |Yun Chen

Oct 27, 2024 | onlinelibrary.wiley.com | Wei Lai |Zhou Ping |Yun Chen |Junrong Wang

1 INTRODUCTION To date, targeted therapy has become one of the preferred methods for treating most cancers.1 However, resistance often occurs during targeted therapy.2 This may be due to the emergence of resistant mutations, compensatory activation of alternative signalling pathways, or the preexistence of cells with dominant growth-carrying resistance gene alterations.

Oct 1, 2024 | journals.plos.org | Yun Chen |Justine Lau |Temerty Faculty |Yasmin Alhamdah

Loading metrics Open Access Peer-reviewedResearch Article Citation: Chen YJ, Lau J, Alhamdah Y, Yan E, Saripella A, Englesakis M, et al. (2024) Changes in health-related quality of life in young-old and old-old patients undergoing elective orthopedic surgery: A systematic review. PLoS ONE 19(10): e0308842. https://doi.org/10.1371/journal.pone.0308842Editor: Raffaele Vitiello, Policlinico Universitario A.