Yung-Hsin Huang

Jul 17, 2024 | nature.com | Patrick Neuhöfer |Julia A. Belk |Yung-Hsin Huang |Lu Chen |Howard Chang

AbstractTelomerase is intimately associated with stem cells and cancer, because it catalytically elongates telomeres—nucleoprotein caps that protect chromosome ends1. Overexpression of telomerase reverse transcriptase (TERT) enhances the proliferation of cells in a telomere-independent manner2,3,4,5,6,7,8, but so far, loss-of-function studies have provided no evidence that TERT has a direct role in stem cell function.

Nov 8, 2023 | nature.com | Yung-Hsin Huang

AbstractThis study was to investigate urinary beta 3-adrenoceptor concentration as a biomarker for overactive bladder (OAB) and predictor of treatment outcomes in women receiving the beta 3-adrenoceptor agonist mirabegron. The study comprised 50 women identified with OAB and 35 women considered as healthy controls. All women with OAB received daily dosage of 50 mg of mirabegron for 12 weeks.