-
Dec 4, 2024 | 
nature.com | Tim Hasenbein |Sarah Hoelzl |Zachary Smith |Chiara Gerhardinger |Oana Amarie |Lore Becker | +9 more
AbstractThe lncRNA Crossfirre was identified as an imprinted X-linked gene, and is transcribed antisense to the trans-acting lncRNA Firre. The Firre locus forms an inactive-X-specific interaction with Dxz4, both loci providing the platform for the largest conserved chromatin structures. Here, we characterize the epigenetic profile of these loci, revealing them as the most female-specific accessible regions genome-wide.
-
Nov 13, 2024 | 
cleveland.com | Zachary Smith
SOUFRIERE, St. Lucia - When visiting a Caribbean island, travelers are often ready to be met with crystal clear waters on beautiful beaches, delicious tropical fruit and exciting water activities. But if you’re someone like me, you also look for adventure when visiting the islands by the Equator. St. Lucia deliversit all, which is how I found myself at the base of Gros Piton on the cusp of one of the most challenging hikes of my life. Don’t get me wrong, I knew what I was getting myself into.
-
Nov 12, 2024 | 
ourcommunitynow.com | Zachary Smith
CLEVELAND, Ohio - One of the oldest members of the Cleveland Cultural Garden is still installing new pieces more than 80 years later. The Carpatho-Rusyn garden, initially dedicated in 1939, installed four informational pedestals on October 2023 to help provide context on Rusyn culture, a map of the region and a list of notable Rusyns. CONTINUE READING
-
Nov 5, 2024 | 
cleveland.com | Zachary Smith
NewsPublished: Nov. 05, 2024, 10:30 a.m.JACK Cleveland Casino in downtown Cleveland on September 10, 2022. David Petkiewicz, cleveland.comDavid Petkiewicz, cleveland.comCOLUMBUS, Ohio — Ohio’s 11 casinos and racinos reported $191 million of gambling revenue in September, $13 million less than in August when it set a monthly record with $204.1 million.
-
Oct 13, 2024 | 
steelersnow.com | Zachary Smith
Welcome to the Steelers Now Postgame, our new daily podcast featuring all the latest Steelers news and analysis. Alan Saunders joins Zachary Smith from Allegiant Stadium to recap the Pittsburgh Steelers’ 32-13 win over the Las Vegas RaidersCheck out the show on our YouTube page, or find it on Megaphone or wherever you get your podcasts. Got a question for the guys?
-
Oct 8, 2024 | 
jdsupra.com | Zachary Smith
The Second Circuit recently a district court’s dismissal for lack of personal jurisdiction in American Girl, LLC’s (“American Girl”) Lanham Act lawsuit against Chinese e-commerce company Zembrka. The Second Circuit held that American Girl established personal jurisdiction under New York’s long-arm statute and that the exercise of personal jurisdiction did not violate due process.
-
Sep 23, 2024 | 
cleveland.com | Zachary Smith
CLEVELAND, Ohio - Does more chemical emissions mean a higher risk to people who live near facilities that handle toxic chemicals? Not necessarily. A cleveland.com and Plain Dealer review of federal data across eight Greater Cleveland counties found that some smaller handlers of toxic chemicals can be the riskiest for the surrounding areas, according to risks scores assigned by the U.S. Environmental Protection Agency.
-
Sep 8, 2024 | 
steelersnow.com | Zachary Smith
Welcome to the Steelers Now Postgame, our new daily podcast featuring all the latest Steelers news and analysis. Alan Saunders joins Smitty live from the Mercedes Benz Stadium following the Steelers season-opening win over the Atlanta Falcons. Check out the show on our YouTube page, or find it on Megaphone or wherever you get your podcasts. Got a question for the guys? Leave a comment on YouTube, here on the website, or find them on Twitter at @ASaunders_PGH and @ZacharySmithPGH
-
Aug 29, 2024 | 
ourcommunitynow.com | Zachary Smith
ShareCLEVELAND, Ohio - Drought conditions have continued to worsen in Ohio, with dry conditions in Ohio spreading despite a few weeks of improvements and two counties in southern Ohio entering drought levels not seen in Ohio since U.S. Drought Monitor records began in 2000.
-
Aug 12, 2024 | 
nature.com | Zachary Smith |Sara Hetzel |Alexander Meissner
AbstractThe DNA methylation field has matured from a phase of discovery and genomic characterization to one seeking deeper functional understanding of how this modification contributes to development, ageing and disease. In particular, the past decade has seen many exciting mechanistic discoveries that have substantially expanded our appreciation for how this generic, evolutionarily ancient modification can be incorporated into robust epigenetic codes.
