Zeyu Guo

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Articles

Quantitatively predicting effects of exercise on pharmacokinetics of drugs using a physiologically based pharmacokinetic model

Sep 9, 2024 | dmd.aspetjournals.org | Zeyu Guo |Jingjing Gao |li Liu |Xiaodong Liu

AbstractExercise significantly alters human physiological functions, such as increasing cardiac output and muscle blood flow, decreasing glomerular filtration rate (GFR) and liver blood flow, thereby, altering absorption, distribution, metabolism and excretion of drugs.

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