Zhanming Zhang

Jun 11, 2024 | chemistry-europe.onlinelibrary.wiley.com | Jie Han |Zhanming Zhang

The formation of carbon-fluorine (C-F) bonds is an important research field in organic synthesis because the insertion of a fluorine atom into an organic compound can alter its physicochemical properties, such as metabolic stability and permeability. Due to this unique property, organic fluorinated compounds, especially aryl fluorides, have a wide range of applications in various fields, including agrochemicals, pharmaceuticals, and materials science.

Mar 9, 2024 | pubs.rsc.org | Chao Fang |Quanpu Wang |Bing Xu |Zhanming Zhang

Palladium/XuPhos-Catalyzed Enantioselective Cascade Heck/ Intermolecular C(sp2)−H Alkylation Reaction Palladium-catalyzed enantioselective domino Heck/intramolecular C-H functionalization reaction, as a valuable strategy for creating molecular diversity, has remained a prominent challenge.