Zhendong Jin

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Articles

Depletion of oxysterol-binding proteins by OSW-1 triggers RIP1/RIP3-independent necroptosis and sensitization to cancer immunotherapy - Cell Death & Differentiation

1 month ago | nature.com | Dongshi Chen |Haibo Qiu |Heinz-Josef Lenz |Zhendong Jin |Jian Yu

AbstractOxysterol-binding proteins (OSBPs), lipid transfer proteins functioning at intracellular membrane contact sites, are recently found to be dysregulated in cancer and promote cancer cell survival. However, their role as potential targets in cancer therapy remains largely unexplored.

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