Jian Yu

1 month ago | nature.com | Dongshi Chen |Haibo Qiu |Heinz-Josef Lenz |Zhendong Jin |Jian Yu

AbstractOxysterol-binding proteins (OSBPs), lipid transfer proteins functioning at intracellular membrane contact sites, are recently found to be dysregulated in cancer and promote cancer cell survival. However, their role as potential targets in cancer therapy remains largely unexplored.

Dec 5, 2024 | biorxiv.org | Qian Wang |Yicheng Guo |Ryan G. Casner |Jian Yu

AbstractSARS-CoV-2 has largely evolved to resist antibody pressure, with each successive viral variant becoming more and more resistant to serum antibodies in the population. This evolution has rendered inactive all therapeutic monoclonal antibodies previously authorized, and it is now threatening the remaining clinical product for immunoprophylaxis against COVID-19.

Nov 7, 2024 | nature.com | Jian Yu |He Huang |Erlie Jiang |Xi Zhang

AbstractAllogeneic hematopoietic stem cell transplantation (allo-HSCT) utilizing mismatched unrelated donors (MMUD) present a vital option for patients with hematologic malignancies without human leukocyte antigen (HLA)-matched donors. This multicenter retrospective study encompassed 211 adults with hematological malignancies receiving allo-HSCT with antithymocyte globulin (ATG) from ≥1 HLA locus MMUD.

Nov 1, 2024 | mdpi.com | Wei Song |Jian Yu

This is an early access version, the complete PDF, HTML, and XML versions will be available soon.

Jun 8, 2024 | mdpi.com | Jian Yu |qiang li

All articles published by MDPI are made immediately available worldwide under an open access license. No specialpermission is required to reuse all or part of the article published by MDPI, including figures and tables. Forarticles published under an open access Creative Common CC BY license, any part of the article may be reused withoutpermission provided that the original article is clearly cited. For more information, please refer tohttps://www.mdpi.com/openaccess.