Zhenqi Zhou

Oct 11, 2024 | dx.doi.org | Zhenqi Zhou |Brihget Sicairos |Jianhong Zhou |Yuchun Du

IntroductionClick to copy section linkSection link copied!Estrogen plays an essential role in the proliferation and differentiation of normal breast tissue and is linked to the development of breast cancer. The main form of estrogen in the cells is 17-β-estradiol (E2). E2 stimulates breast cell proliferation by binding to estrogen receptor alpha (ERα) thereby altering estrogen-responsive gene expression that regulates the cell cycle and apoptosis.

Oct 11, 2024 | pubs.acs.org | Zhenqi Zhou |Brihget Sicairos |Jianhong Zhou |Yuchun Du

IntroductionClick to copy section linkSection link copied!Estrogen plays an essential role in the proliferation and differentiation of normal breast tissue and is linked to the development of breast cancer. The main form of estrogen in the cells is 17-β-estradiol (E2). E2 stimulates breast cell proliferation by binding to estrogen receptor alpha (ERα) thereby altering estrogen-responsive gene expression that regulates the cell cycle and apoptosis.