Zhichao Lu

Jul 19, 2024 | science.org | Ruiyi Zhang |Aashish Gupta |Zhichao Lu |Min Zhu |Chenxing Wang |Rui Jiang | +10 more

AbstractAged patients often suffer poorer neurological recovery than younger patients after traumatic brain injury (TBI), but the mechanisms underlying this difference remain unclear. Here, we demonstrate abnormal myelopoiesis characterized by increased neutrophil and classical monocyte output but impaired nonclassical patrolling monocyte population in aged patients with TBI as well as in an aged murine TBI model.

Apr 5, 2024 | nature.com | Zhichao Lu

AbstractClass I KNOTTED-like homeobox (KNOXI) genes are parts of the regulatory network that control the evolutionary diversification of leaf morphology. Their specific spatiotemporal expression patterns in developing leaves correlate with the degrees of leaf complexity between simple-leafed and compound-leafed species. However, KNOXI genes are not involved in compound leaf formation in several legume species.