Aashish Gupta

Dec 2, 2024 | medium.com | Aashish Gupta

Aashish Gupta·Follow3 min read·--Coralie Fargeat’s Substance is one of those films that refuses to leave your consciousness, a visceral experience that lingers long after the credits roll. It’s a work of art that disturbs, mesmerizes, and challenges the viewer’s emotional and psychological boundaries. It is the rare kind of film that pushes you into a space where you simultaneously recoil in discomfort yet cannot look away.

Oct 24, 2024 | medium.com | Aashish Gupta

Aashish Gupta·Follow2 min read·--Funny Games (1997), a Michael Haneke experimental masterpiece, is one of those films that lingers in your mind long after you’ve watched it, but not necessarily for reasons you’d expect. Contrary to its title, Funny Games is not funny at all — it’s unapologetically dark and can be a difficult watch for some. The title almost feels like a cruel joke, luring the audience into a false sense of security before pulling the rug out from under them.

Jul 19, 2024 | science.org | Ruiyi Zhang |Aashish Gupta |Min Zhu |Zhenyu Zhou

AbstractFor wearable electronics, radial scalability is one of the key research areas for fibrous energy storage devices to be commercialized, but this field has been shelved for years due to the lack of effective methods and configuration arrangements. Here, the team presents a generalizable strategy to realize radial scalability by applying a synchronous-twisting method (STM) for synthesizing a coaxial-extensible configuration (CEC).

Jul 19, 2024 | science.org | Ruiyi Zhang |Aashish Gupta |Min Zhu |Manisha C. Yadav

AbstractHuntingtin protein, mutated in Huntington’s disease, is implicated in nucleic acid–mediated processes, yet the evidence for direct huntingtin–nucleic acid interaction is limited. Here, we show wild-type and mutant huntingtin copurify with nucleic acids, primarily RNA, and interact directly with G-rich RNAs in in vitro assays.

Jul 19, 2024 | science.org | Ruiyi Zhang |Aashish Gupta |Zhichao Lu |Min Zhu |Chenxing Wang |Rui Jiang | +10 more

AbstractAged patients often suffer poorer neurological recovery than younger patients after traumatic brain injury (TBI), but the mechanisms underlying this difference remain unclear. Here, we demonstrate abnormal myelopoiesis characterized by increased neutrophil and classical monocyte output but impaired nonclassical patrolling monocyte population in aged patients with TBI as well as in an aged murine TBI model.