Zhigang Chen

Nov 29, 2024 | molecular-cancer.biomedcentral.com | Menglei Jin |Jun Fang |Junwen Peng |Xintian Tina Wang |Ping Ping Xing |Kunpeng Jia | +6 more

Tumor-infiltrating lymphocytes (TILs) have emerged as a readily available and effective marker for assessing tumor immune profiles (Fig. 4). The pathological evaluation of TILs offers a convenient approach to identifying patients who are likely to respond favorably to immunotherapy. For instance, a randomized trial found that a TIL level of ≥ 5% could predict a positive response to pembrolizumab.

Dec 13, 2023 | nature.com | Zhigang Chen

NEWS AND VIEWS 13 December 2023 Ultrathin semiconductor materials that mimic twisted layers of atoms have been used to build synchronized arrays of nanometre-scale lasers. The systems can be configured — and easily reconfigured — to form intricate patterns. It might seem straightforward to make a bright light source by combining multiple lasers but, in reality, it is tremendously complex.

Oct 21, 2023 | pubs.rsc.org | Zhigang Chen |Qin Jiang |Hao Xu |Wen Zhang

Mn (II)-Hemoporfin-based metal-organic frameworks as a theranostic nanoplatform for MRI-guided sonodynamic therapy Imaging-guided therapy holds great potential for enhancing therapeutic performance in a personalized way. However, it is still challenging to develop appropriate multifunctional materials to overcome the limitations of current all-in-one theranostic agents.

Sep 2, 2023 | nature.com | Zhigang Chen

AbstractThe lack of available protons severely lowers the activity of alkaline hydrogen evolution reaction process than that in acids, which can be efficiently accelerated by tuning the coverage and chemical environment of protons on catalyst surface. However, the cycling of active sites by proton transfer is largely dependent on the utilization of noble metal catalysts because of the appealing electronic interaction between noble metal atoms and protons.

Aug 31, 2023 | onlinelibrary.wiley.com | Zhigang Chen |Yamei Wang |Liyong Yang |Shuo Liu

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