Ziyue Zhu

2 months ago | advanced.onlinelibrary.wiley.com | Surya Prakash |Ziyue Zhu |Jiaqi Tang |Matthew Coe

An operationally simple protocol to access 2,2-chlorofluoro-, and 2,2-bromofluorobicyclopentanes (BCPs) via commercially available, inexpensive, non-ozone depleting, and bench stable reagents is reported. The resulting BCP products are tolerated in diverse, synthetically relevant post-functionalization reactions. Gram-scale reactions to prepare the BCPs are also included.