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Topical Analgesics for Neuropathic Pain: What’s Best?

1 week ago | medcentral.com | Kathleen Doheny

Neuropathic pain affects approximately 8% of US adults, and while pharmacotherapy can ease symptoms, only 40% to 60% of patients report pain relief with medication. And many would rather use a topical agent instead of an oral pill, pain medicine experts find. The problem for physicians and pharmacists is that there is no current clinical guidance regarding best practices for topical selection or on the types of neuropathic pain for which a topical may work best.
Combined Cardiovascular and Kidney Problems on the Rise

1 week ago | medcentral.com | Avery Hurt |Barbara Hazelden |Oladimeji Ewumi |Racheal Ede

Increasing numbers of adults are experiencing a progressive syndrome driven by the interaction of chronic kidney disease and cardiovascular disease, obesity, and other metabolic factors, based on data from a new review presented at the National Kidney Foundation Spring Clinical Meeting in Boston. What is Cardiovascular-Kidney-Metabolic Syndrome?
Fibromyalgia: Mayo’s Emerging Gold Standard Treatment

1 week ago | medcentral.com | Kathleen Doheny

Without a cure, the focus of fibromyalgia treatment is symptom management, yet even still, many patients do not experience symptom relief. This was a core message delivered by Arya Mohabbat, MD, at the American Academy of Pain Medicine PainConnect 2025 meeting in Austin, TX.
How to Use JAK Inhibitors to Treat IMIDs: Updated Consensus Statement

2 weeks ago | medcentral.com | Kimberly Bjugstad

A new international consensus statement on the treatment of immune-mediated inflammatory diseases with Janus kinase inhibitors was published online last month in Annals of the Rheumatic Diseases, providing a key update to the prior 2019 statement.1,2 Put together by an international committee of rheumatology experts, the new statement provides a much-needed update given that several new Janus kinase inhibitors (JAKi) have been approved since 2019, many of them being indicated for...
Arthritis Linked to Overactive Bladder, per New Study

2 weeks ago | medcentral.com | Heidi Splete

Osteoarthritis and overactive bladder are both common conditions and, based on new study data, closely related. A research team based in China found a positive association between arthritis and overactive bladder (OAB) in a logistic regression analysis, with an odds ratio of 1.37. The team used data from the National Health and Nutrition Examination Survey (NHANES) database from 2005 to 2020, with a final study population including 24,436 individuals aged 20 years and older.
Practice Change for Cancer Patients at Risk for Venous Thromboembolism

2 weeks ago | medcentral.com | Patrice Wendling |Suchandrima Bhowmik |Youssef Rddad

Extended treatment with a lower dose of apixaban (Eliquis) is noninferior to the full dose at preventing recurrent venous thromboembolism (VTE) with less bleeding in patients with active cancer who have completed at least 6 months of anticoagulation therapy, results from the API-CAT trial show. Findings were presented at the American College of Cardiology Annual Scientific Session and simultaneously published in the New England Journal of Medicine.
Will AI-Driven Care Change Medical Practice?

3 weeks ago | medcentral.com | Lauren Hunter |Aaron Tallent

A digital stethoscope that can detect pathologic murmurs in patients. AI speaking with AI to resolve a prior authorization request. These are just some of the artificial intelligence (AI)-powered tools being deployed in medical practices across the country. Here is a closer look. Stethoscopes that Detect Heart DiseaseTo support physicians at the care level, Eko Health has reimagined a device used in medicine for more than 200 years.
WARRIOR: Battle Goes on for Optimal Treatment of INOCA

3 weeks ago | medcentral.com | Susan Redline |Angie Drakulich |Avery Hurt |Patrice Wendling

Intensive medical treatment did not reduce the risk of major adverse cardiovascular events (MACE) at 5 years compared with usual care among women with ischemia and nonobstructive coronary artery disease in the WARRIOR trial. Results were presented at the American College of Cardiology (ACC25) annual meeting and are under review by JAMA.
ADVANCE-HTN: Evidence Builds for Lorundrostat in Resistant Hypertension

3 weeks ago | medcentral.com | Angie Drakulich |Heidi Splete |Avery Hurt |Patrice Wendling

Once-daily, add-on treatment with the aldosterone synthase inhibitor lorundrostat significantly reduced blood pressure in adults with uncontrolled and treatment-resistant hypertension in a second pivotal trial, ADVANCE-HTN. Results were presented at the American College of Cardiology annual scientific session (ACC.25) this past weekend and are accepted for publication in the New England Journal of Medicine.
Vitiligo Comorbidities and Confounding Factors Examined

4 weeks ago | medcentral.com | Lauren Hunter |Racheal Ede

A correlation between demographic and socioeconomic factors and the incidence of comorbid depression, anxiety, or hypothyroidism in individuals with vitiligo was demonstrated in recent research conducted by a team at Baylor College of Medicine. The study was presented at the Skin of Color Society’s Scientific Symposium in Orlando, FL, where it won third place for abstracts advancing skin of color dermatology.