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Extended CT Scan Use in Acute Ischemic Stroke Could Greatly Improve Outcomes

1 week ago | medcentral.com | Susan Kreimer

Within minutes of a patient’s arrival to a hospital with an acute ischemic stroke, using extended CT imaging that also scans the heart could greatly aid in accurate diagnosis and patient outcomes, a new study suggests. By identifying a stroke’s underlying cause, the extended imaging was found to lower the proportion of patients classified as having strokes of unspecific origin after standard diagnostic workup.
Superior IBS Symptom Improvement with Low-FODMAP

1 week ago | medcentral.com | Oladimeji Ewumi

The low-FODMAP diet confers greater symptomatic relief in people with diarrhea or mixed subtypes of irritable bowel syndrome compared to the Mediterranean diet, according to a study published in Neurogastroenterology & Motility. “This is the first trial to compare the Mediterranean diet with an active intervention, the low-FODMAP diet,” Prashant Singh, MBBS, lead author and assistant professor of medicine at the University of Michigan Health in Ann Arbor, told MedCentral.
Single-Dose RTX Shows Promise in Intractable Cancer Pain

1 week ago | medcentral.com | Suchandrima Bhowmik

Resiniferatoxin (RTX), a small, plant-derived agonist of the transient receptor potential vanilloid 1 (TRPV1) ion channel, was shown to reduce intractable pain in patients with advanced cancer in an interim study published in NEJM Evidence. “TRPV1, the receptor for RTX, is a molecule located in pain-sensing nerve endings in the skin and deep tissues.
Survey Shows One-Third of Physicians Considering Leaving Medicine

1 week ago | medcentral.com | Marcia Frellick

More than one-third of physicians (35%) who responded to a MedCentral survey said they have considered leaving medical practice since the start of 2025. Among those considering leaving, the top reason was personal burnout (cited by 31%), followed by early retirement (20%), on-time retirement (16%), and clinical demands (15%).
As Pressures Mount, Many Physicians May Quit: Report Shows Concerns Rising

1 week ago | medcentral.com | Angie Drakulich

IntroductionFrom new healthcare policies to technology advances, the field of medicine continues to evolve, but not everyone is happy. In MedCentral’s second annual national survey, physicians shared how they are adapting to these significant changes and if the changes are making them think again about their chosen career. The following results are based on over 1,100 physician responses.
Michael Chandler Honored with 2025 Fudin Award for Pain and Palliative Mentorship

1 week ago | medcentral.com | Angie Drakulich

MedCentral is pleased to share the recipient of the 2025 Fudin Award for Pain and Palliative Care Mentorship, presented by the SPPCP Foundation: Michael Chandler, PharmD, BCGP. This award was developed in partnership with the Society of Pain & Palliative Care Pharmacists Foundation (SPPCP Foundation) in 2022 in the name of Jeffrey Fudin, PharmD, FCCP, FASHP, FFSMB.
An Honest Conversation on Moving Up

2 weeks ago | medcentral.com | Michelle Lee |Angie Drakulich

In this episode of Moving Ahead in Medicine, host Michelle Lee, MD, engages in one last conversation on being an early-career physician as she moves into an attending role in New York City. Not being the only “imposter” in medicine is perhaps her biggest lesson learned. Listen to the conversation or read the lightly edited transcript below. Listen On: Amazon | Apple | SpotifyTranscriptDrakulich: Welcome back to Moving Ahead in Medicine.
Muting Alcohol Behaviors Using GLP-1 Agonists

3 weeks ago | medcentral.com | Kimberly Bjugstad

Glucagon-like peptide-1 (GLP-1) agonists, such as semaglutide or liraglutide, are widely used for supporting diabetic and weight management.1 Somatically, GLP-1 directs pancreatic insulin release and suppresses secretion of glucagon to balance blood sugar levels.2,3 However, there is a small neuronal population in the caudal medulla that also releases GLP-1, with action in the hypothalamus, assisting in regulating homeostatic feeding, and in the ventral tegmental area (VTA), which is involved...
CKM Severity Associated with Sleep Health and Smoking

3 weeks ago | medcentral.com | Racheal Ede

A pair of recent studies examined the impact of common risk factors – sleep quality and smoking status – on kidney and cardiovascular disease in individuals at various stages of cardiovascular kidney metabolic syndrome. Sleep Quality May Amplify CKM SeverityIn a nationally representative cross-sectional study, people with moderate and high sleep quality had a 32% and 45% lower risk, respectively, of being in advanced stages of cardiovascular kidney metabolic (CKM) syndrome.
Are Oncologists Undertreating Pain in Cancer Patients? New Data Raise Questions

3 weeks ago | medcentral.com | Leah Lawrence

Opioid prescriptions for cancer pain significantly decreased during the five-year period from 2016 to 2021 among a sample of outpatients at a single tertiary cancer center, according to a recent study published in JCO Oncology Practice. Specifically, the number of patients who had not been prescribed any opioids increased from 28% in 2016 to 41% in 2021 (P=.008).