Rheumatology Advisor

http://RheumatologyAdvisor.com provides healthcare specialists with a valuable resource filled with practical information on rheumatology to aid in their clinical decision-making. Our goal is to support rheumatology professionals by offering detailed and relevant clinical and medication information that aligns with the latest care principles, enabling clinicians to enhance patient outcomes effectively.

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Noncigarette Tobacco Products Associated With Subclinical Cardiovascular Harm

2 days ago | rheumatologyadvisor.com | Colby Stong

Noncigarette tobacco products are associated with subclinical inflammation, thrombosis, and atherosclerosis markers, according to results of a study published in Circulation. Researchers analyzed data from the Cross-Cohort Collaboration-Tobacco (CCC-Tobacco) Working Group. The cross-sectional analysis included cohorts with data for use of 1 or more noncigarette tobacco product (cigar, pipe, or smokeless tobacco) and measurement for 1 or more of 8 subclinical markers in the same visit.
Fibromyalgia Diagnoses Declined Following 2016 Update to ACR Diagnostic Criteria

3 days ago | rheumatologyadvisor.com | Lisa M Kuhns

Fibromyalgia diagnoses among patients in ambulatory settings increased after 2010 and then declined after 2016, with both events following the release of updated diagnostic criteria from the American College of Rheumatology (ACR). Although the latest update maintains rheumatoid arthritis and major depressive disorder as key comorbidities in fibromyalgia, it may lack the sensitivity to other comorbidities provided by the 2010 criteria. These study results were published in BMC Rheumatology.
Depression, Female Sex, and Axial Disease Predict Multi-b/tsDMARD Failure in PsA

4 days ago | rheumatologyadvisor.com | Lisa M Kuhns

Patients with psoriatic arthritis (PsA) who fail multiple biologic and targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs) face significant challenges in achieving disease control, with higher risks associated with depression, female sex, obesity, and axial disease, according to study results published in Arthritis Research & Therapy.
Metabolic Syndrome Linked to Degenerative Spinal Changes in PsA

4 days ago | rheumatologyadvisor.com | Lisa M Kuhns

Metabolic syndrome (MetS) is significantly associated with certain degenerative changes among patients with psoriatic arthritis (PsA) — particularly plantar and/or Achilles calcaneal spurs, diffuse idiopathic skeletal hyperostosis (DISH), and degenerative disc disease (DDD) — but not with peripheral or axial joint damage, according to study results published in Arthritis Care & Research.
Early Steroid Tapering in Kawasaki Disease Shows Comparable Outcomes to Standard Protocols

1 week ago | rheumatologyadvisor.com | Hibah Khaja

An early steroid tapering protocol for high-risk patients with Kawasaki disease (KD) showed comparable rates of symptom recurrence and coronary artery lesions (CALs) when compared with traditional prolonged steroid regimens, according to study results published in Rheumatology. While adjunctive corticosteroids have shown benefits among high-risk patients with KD, the optimal duration of steroid therapy remains uncertain.
Colchicine Use in FMF Not Linked to Increased Reproductive Risks

1 week ago | rheumatologyadvisor.com | Hibah Khaja

Colchicine is not associated with a significant increase in adverse reproductive outcomes among patients with familial Mediterranean fever (FMF), according to study findings published in Annals of the Rheumatic Diseases. Despite colchicine’s effectiveness for managing FMF, concerns have been raised about its potential teratogenic effects, impact on fertility, and safety during breastfeeding.
Gender Dysphoria in Transgender Men Associated With Seeking Cosmetic Procedures

1 week ago | rheumatologyadvisor.com | Colby Stong

Transgender men have increased rates of gender dysphoria compared with transgender women, affecting their decision to have a cosmetic dermatologic procedure, according to study results presented at the American Academy of Dermatology (AAD) 2025 Annual Meeting, held in Orlando, Florida, from March 7 to 11. Researchers conducted a survey to assess which cosmetic dermatologic procedures are sought out by transgender patients and the reasons for pursuing care.
Systemic Lupus Erythematosus Increases Risk for Pulmonary Manifestations

1 week ago | rheumatologyadvisor.com | Lisa M Kuhns

Systemic lupus erythematosus (SLE) may increase the risk for pulmonary manifestations, including interstitial lung disease (ILD), pulmonary hypertension, and pleural disorders, according to study results published in RMD Open. Researchers conducted a population-based longitudinal cohort study using data from the Korean National Health Insurance Service, which includes comprehensive health records for nearly 50 million individuals.
Maternal Anti-Ro Antibodies Do Not Impact Autoimmune Disease Prevalence in Offspring

1 week ago | rheumatologyadvisor.com | Lisa M Kuhns

Children born to anti-Ro antibody-positive mothers do not exhibit a significantly increased risk for allergic, neurodevelopmental, or autoimmune conditions compared with the general population, according to study results published in Arthritis Care & Research. Researchers in Toronto, Canada, conducted a cohort study to assess the prevalence of allergic, neurodevelopmental, and autoimmune (rheumatic and nonrheumatic) conditions among children born to anti-Ro antibody-positive mothers.
Long-Term Mepolizumab Use in EGPA Is Safe, Reduces Corticosteroid Dependence

1 week ago | rheumatologyadvisor.com | Hibah Khaja

Long-term treatment with mepolizumab, an interleukin-5 inhibitor, demonstrates a favorable safety profile and sustained corticosteroid-sparing benefits among patients with eosinophilic granulomatosis with polyangiitis (EGPA), according to study findings published in Arthritis & Rheumatology. While effective, prolonged oral corticosteroid (OCS) use for managing EGPA is associated with significant adverse effects.