The Analytical Scientist

This initial editorial outlines the goals and aspirations of the publication and its website.

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Articles

Spatial Proteomics Advance Liver Cancer Prognostics

1 week ago | theanalyticalscientist.com | Helen Bristow

The prognostic power of spatial proteomics has given rise to a new tool for predicting the recurrence of hepatocellular carcinoma (HCC) after resection surgery. The system, described in , uses AI to interrogate the distribution of natural killer (NK) cells in the tumor microenvironment and identify high-risk patients. Here, corresponding author Joe Yeong shares details of the study, the prognostic scoring system that was developed, and its potential impact for patients with liver cancer.
This Week’s Spectroscopy News

3 weeks ago | theanalyticalscientist.com | James Strachan

Is the Atomic Spectra Database Under Threat? There was more news this week from the US of the Trump administration’s cost-cutting plans – this time affecting the spectroscopy community; specifically, the US Institute of Standards and Technology (NIST)’s Atomic Spectroscopy Group, according to an email sent to dozens of outside scientists, reports Wired.
What If Computers Could Smell?

3 weeks ago | theanalyticalscientist.com | James Strachan

With Laurianne ParavisiniI was originally trained as an analytical chemist. I started my studies in France in analytical chemistry, and then I transitioned into the world of odors and flavors. During an internship, I worked on odor emissions from car seats, which is important for consumer purchases – what your new car smells like. It also has health implications regarding the compounds being released.
Why We’re Turning the 2025 Power List on its Head

1 month ago | theanalyticalscientist.com | James Strachan

Each year, we ask the individuals on our Power List about the biggest challenges facing analytical science; raising the profile of the field, attracting talent, and data overload often come up. In 2025, add to the list economic and political turmoil – and especially uncertainty around research funding – which present their own serious difficulties while also amplifying those existing challenges. The future flourishing of the field is more uncertain than ever.
Deeper Potential for Extracellular Vesicle Detection

1 month ago | theanalyticalscientist.com | Jessica Allerton

A novel high-throughput nanoparticle detection method, Deep Nanometry (DNM), has demonstrated high sensitivity and scalability in detecting rare extracellular vesicles (EVs) without purification – showcasing its potential in advancing early cancer diagnostics.
This Week’s Spectroscopy News

1 month ago | theanalyticalscientist.com | James Strachan

This week, we came across three papers demonstrating spectroscopy’s potential to improve disease diagnosis, surgical precision, and post-surgery care – in three different diseases – which we thought made for a pleasing juxtaposition. The first, a review paper, examined the role of infrared spectroscopy and machine learning for head and neck cancer – the seventh most common cancer worldwide – and precancer diagnosis.
Bye, Bye ELISA?

1 month ago | theanalyticalscientist.com | Jessica Allerton

Over 850 million people worldwide are affected by kidney disease – more than double those living with diabetes. Though various diagnostic methods are used in clinical settings, they can be invasive, expensive, and uncomfortable. Researchers at Chung-Ang University, South Korea, tackled the issue head on, developing an innovative diagnostic method based on a peptide receptor that specifically binds to symmetric dimethylarginine (SDMA) – a key biomarker of kidney disease (1).
This Week’s Spectroscopy News

1 month ago | theanalyticalscientist.com | James Strachan

This year’s Coblentz Society Williams-Wright Award goes to… David W. Schiering – a scientist-entrepreneur who has spent his nearly 40-year career developing vibrational spectroscopy instruments and methods. He is now a 908 Devices Fellow at 908 Devices. Schiering’s opening talk at 8:40am on Wednesday is followed by a presentation from David’s 908 Devices colleague, Christopher Brown.
Do Scientists Really Need Another Twitter?

2 months ago | theanalyticalscientist.com | James Strachan

It’s a new year and that may mean new diets, exercise routines, and productivity plans. But what about a “Twitter break” – or perhaps an X-odus? Elon Musk’s “handling” of the platform has led to considerable soul searching as many, including those in the analytical science community, ponder migrating to microblogging alternative Bluesky – indeed many already have. But I’m beginning to wonder whether scientists really need another Twitter.
P-tau: Predictor and Protector in Alzheimer’s

Jan 27, 2025 | theanalyticalscientist.com | Jessica Allerton

A recent study in Cell Reports highlights the diagnostic potential of phosphorylated tau (p-tau) in Alzheimer’s disease (AD) as well as its role in defending against herpes simplex virus-1 (HSV-1). Researchers from the University of Pittsburgh and Hebrew University of Jerusalem employed advanced imaging techniques and in vitro models to investigate the interactions between p-tau and HSV-1, highlighting implications for innate immune responses in neurodegenerative diseases.