Adam C Gunning

Apr 26, 2024 | genomemedicine.biomedcentral.com | Robin Beaumont |Gareth Hawkes |Adam C Gunning |Caroline Wright

Variants from exome sequencing (ES) data within the UK Biobank were called centrally by the UKB team using graphTyper [19]. We used the Ensembl VEP v104 [20] with the LOFTEE plugin [15] to annotate the variants with their predicted functional consequences. We excluded variants which were flagged for removal by UKB due to low depth based on 90% of calls having depth < 10.

Oct 12, 2023 | medrxiv.org | Robin Beaumont |Gareth Hawkes |Adam C Gunning |Caroline Wright

The authors have declared no competing interest. This work was supported by the Medical Research Council [MR/T00200X/1]I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.