Adam L Boxer

2 months ago | nature.com | Cyril Pottier |Fahri Küçükali |Matt Baker |Gregory Jenkins |Cristina T. Vicente |Wouter De Coster | +55 more

AbstractFrontotemporal lobar degeneration with neuronal inclusions of the TAR DNA-binding protein 43 (FTLD-TDP) is a fatal neurodegenerative disorder with only a limited number of risk loci identified.

Aug 10, 2023 | nature.com | Murray Grossman |Adam L Boxer |David S. Knopman |Henrik Zetterberg

AbstractFrontotemporal lobar degeneration (FTLD) is one of the most common causes of early-onset dementia and presents with early social–emotional–behavioural and/or language changes that can be accompanied by a pyramidal or extrapyramidal motor disorder. About 20–25% of individuals with FTLD are estimated to carry a mutation associated with a specific FTLD pathology.