
Fahri Küçükali
Articles
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1 month ago |
nature.com | Cyril Pottier |Fahri Küçükali |Matt Baker |Gregory Jenkins |Cristina T. Vicente |Wouter De Coster | +55 more
AbstractFrontotemporal lobar degeneration with neuronal inclusions of the TAR DNA-binding protein 43 (FTLD-TDP) is a fatal neurodegenerative disorder with only a limited number of risk loci identified.
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Jul 21, 2024 |
medrxiv.org | Fahri Küçükali |Elizabeth Hill |Tijs Watzeels |Holger Hummerich
AbstractBackground and ObjectivesPrions are misfolded prion protein assemblies that cause several fatal and transmissible neurodegenerative diseases, with the most common phenotype in humans being sporadic Creutzfeldt-Jakob disease (sCJD). However, aside from the prion protein itself, molecular risk factors are not well understood. Prion and prion-like mechanisms are thought to underpin common neurodegenerative disorders meaning that the elucidation of mechanisms could have broad relevance.
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