Gregory Jenkins

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Articles

Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing - Nature Communications

1 month ago | nature.com | Cyril Pottier |Fahri Küçükali |Matt Baker |Gregory Jenkins |Cristina T. Vicente |Wouter De Coster | +55 more

AbstractFrontotemporal lobar degeneration with neuronal inclusions of the TAR DNA-binding protein 43 (FTLD-TDP) is a fatal neurodegenerative disorder with only a limited number of risk loci identified.
Pharmacogenomic overlap between antidepressant treatment response in major depression & antidepressant associated treatment emergent mania in bipolar disorder | Translational Psychiatry

Feb 12, 2024 | nature.com | Brandon J Coombes |Marin Veldic |Balwinder Singh |Mete Ercis |Gregory Jenkins |Jonathan Leung | +3 more

AbstractThere is increasing interest in individualizing treatment selection for more than 25 regulatory approved treatments for major depressive disorder (MDD). Despite an inconclusive efficacy evidence base, antidepressants (ADs) are prescribed for the depressive phase of bipolar disorder (BD) with oftentimes, an inadequate treatment response and or clinical concern for mood destabilization.

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