Adrienne Boire

Jan 22, 2025 | onclive.com | D. Ross Camidge |Adrienne Boire

CommentaryPodcastJanuary 22, 2025Author(s):,Drs Camidge and Boire discuss Dr Boire's path to becoming a physician-scientist and how cellular biology research can improve outcomes for patients with cancer. How This Is Building Me, hosted by world-renowned oncologist D. Ross Camidge, MD, PhD, is a podcast focused on the highs and lows, ups and downs of all those involved with cancer, cancer medicine, and cancer science across the full spectrum of life’s experiences.

Nov 15, 2024 | cell.com | Ján Remšík |KU Leuven |Adrienne Boire

Get full text accessLog in, subscribe or purchase for full access. References1. Long, G.V. ∙ Atkinson, V. ∙ Lo, S. ... Combination nivolumab and ipilimumab or nivolumab alone in melanoma brain metastases: a multicentre randomised phase 2 studyLancet Oncol. 2018; 19:672-6812. Tawbi, H.A. ∙ Forsyth, P.A. ∙ Algazi, A. ... Combined Nivolumab and Ipilimumab in Melanoma Metastatic to the BrainN. Engl. J. Med. 2018; 379:722-7303. Wang, C. ∙ Zeng, Q. ∙ Gul, Z.M. ...

Jun 19, 2024 | nature.com | Adrienne Boire |Thomas Cox |Tobias Janowitz |Rebecca Lee |Charles Swanton

AbstractCancer is a major cause of global mortality, both in affluent countries and increasingly in developing nations. Many patients with cancer experience reduced life expectancy and have metastatic disease at the time of death. However, the more precise causes of mortality and patient deterioration before death remain poorly understood.

Jun 13, 2024 | nature.com | Ján Remšík |Adrienne Boire

AbstractThe leptomeninges, the cerebrospinal-fluid-filled tissues surrounding the central nervous system, play host to various pathologies including infection, neuroinflammation and malignancy. Spread of systemic cancer into this space, termed leptomeningeal metastasis, occurs in 5–10% of patients with solid tumours and portends a bleak clinical prognosis. Previous, predominantly descriptive, clinical studies have provided few insights.

Feb 5, 2023 | onlinelibrary.wiley.com | Inna Smalley |Adrienne Boire |Priscilla K Brastianos |Harriet M Kluger

1 INTRODUCTION Multiple therapeutic advances have substantially improved the prognosis for patients with metastatic melanoma. However, metastasis to the central nervous system (CNS) remains a common, morbid, and highly lethal challenge.