Aihui Wang

Aug 23, 2024 | nature.com | Christine Yeh |Olivia Laveroni |Subin Kim |Aihui Wang |Brooke Liang |Raeline Valbuena | +4 more

AbstractThe drivers of immune evasion are not entirely clear, limiting the success of cancer immunotherapies. Here we applied single-cell spatial and perturbational transcriptomics to delineate immune evasion in high-grade serous tubo-ovarian cancer. To this end, we first mapped the spatial organization of high-grade serous tubo-ovarian cancer by profiling more than 2.5 million cells in situ in 130 tumors from 94 patients.

Jul 4, 2024 | agupubs.onlinelibrary.wiley.com | Xin Ma |Aihui Wang

1 Introduction Terrestrial hydrology is pivotal in the climate system, directly affecting the ecosystem, industry, agriculture, and human activities. In the context of global climate change, the trends in most hydrological variables have a warming-induced intensification at regional to continental scales (Huntington, 2006). Numerical models are essential tools for simulating historical climate and projecting future climate change (Jiang et al., 2016; Sillmann et al., 2013).